Doxofylline is a xanthine derivative that inhibits phosphodiesterases (PDEs), but does not activate adenosine receptors. Doxofylline exhibits anti-asthma, anti-tussive, and bronchodilatory activities and is clinically used to treat asthma.
| Cas No. | 69975-86-6 |
|---|---|
| Purity | ≥98% |
| Formula | C11H14N4O4 |
| Formula Wt. | 266.25 |
| Chemical Name | 7-(1,3-Dioxolan-2-yl-methyl)-3,7-dihydro-1,3- dimethyl-1H-purine-2,6-dione |
| IUPAC Name | 7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione |
| Synonym | Ansimar; Maxivent; Ventax |
| Melting Point | 144-145.5°C |
| Solubility | Soluble in water, acetone, ethyl acetate, hot methanol, hot ethanol, benzene or chloroform. |
| Appearance | White Crystal Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | D5792 MSDS PDF |
|---|---|
| Info Sheet | D5792 Info Sheet PDF |
Shukla D, Chakraborty S, Singh S, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10(14):2343-56. PMID: 19678793.
Cirillo R, Barone D, Franzone JS. Doxofylline, an antiasthmatic drug lacking affinity for adenosine receptors. Arch Int Pharmacodyn Ther. 1988 Sep-Oct;295:221-37. PMID: 3245738.
LKT Labs
LKT实验室是一家专注于小分子的合成、纯化和分离的生化供应公司，用于研究应用。它的产品系列展示了已知的生物活性，在广泛的研究领域，特别是癌症和神经科学中得到了广泛的应用。这些产品包括蛋白激酶抑制剂、离子通道调节剂和激活剂。
LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators.
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品牌 |
货号 |
名称 |
规格 |
|
LKT Labs |
444912-48-5 |
(2-iodo-5-nitrophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone |
1mg 5mg 25mg |
|
LKT Labs |
294646-77-8 |
(R)-CR8 |
1mg 5mg |
|
LKT Labs |
2377-31-3 |
(Z)-1,-BIS(2-METHOXY-5-(TRIFLUOROMETHYL)PHENYL)DIAZENE OXIDE |
1mg 5mg 25mg |
