Oxolinicacidisafluoroquinoloneantibioticthatisusedinplantsandveterinarymedicine;it’santibacterialefficacystemsfrominhibitionofbacterialDNAgyrase.Whencombinedwithmetalssuchasruthenium,manganese,nickel,orzinc,themetal-oxolinicacidcomplexintercalateswithDNA.Additionally,oxolinicacidmaylowerthethresholdforinductionofseizurethroughactivationofexcitatoryaminoacidreceptors.
| CasNo. | 14698-29-4 |
|---|---|
| Purity | ≥98% |
| Formula | C13H11NO5 |
| FormulaWt. | 261.23 |
| IUPACName | 5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylicacid |
| Appearance | WhitePowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | O9458MSDSPDF |
|---|---|
| InfoSheet | O9458InfoSheetPDF |
KljunJ,BratsosI,AlessioE,etal.Newusesforolddrugs:attemptstoconvertquinoloneantibacterialsintopotentialanticanceragentscontainingruthenium.InorgChem.2013Aug5;52(15):9039-52.PMID:23886077.
TarushiA,LafazanisK,KljunJ,etal.First-andsecond-generationquinoloneantibacterialdrugsinteractingwithzinc(II):structureandBIOLOGicalperspectives.JInorgBiochem.2013Apr;121:53-65.PMID:23353082.
KwonHR,ChoiGJ,ChoiYH,etal.Suppressionofpinewiltdiseasebyanantibacterialagent,oxolinicacid.PestManagSci.2010Jun;66(6):634-9.PMID:20151406.
WilliamsPD,HeltonDR.Theproconvulsiveactivityofquinoloneantibioticsinananimalmodel.ToxicolLett.1991Sep;58(1):23-8.PMID:1897004.
LKT Labs
LKT实验室是一家专注于小分子的合成、纯化和分离的生化供应公司，用于研究应用。它的产品系列展示了已知的生物活性，在广泛的研究领域，特别是癌症和神经科学中得到了广泛的应用。这些产品包括蛋白激酶抑制剂、离子通道调节剂和激活剂。
LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators.
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品牌 |
货号 |
名称 |
规格 |
|
LKT Labs |
444912-48-5 |
(2-iodo-5-nitrophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone |
1mg 5mg 25mg |
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LKT Labs |
294646-77-8 |
(R)-CR8 |
1mg 5mg |
|
LKT Labs |
2377-31-3 |
(Z)-1,-BIS(2-METHOXY-5-(TRIFLUOROMETHYL)PHENYL)DIAZENE OXIDE |
1mg 5mg 25mg |
