Growth hormone releasing factor (GHRF or GHRH) is an endogenous peptide hormone that binds the GHRH receptor in the anterior pituitary, inducing the release of growth hormone. GHRF promotes non-REM slow wave sleep in animal models. Additionally, GHRF decreases fat synthesis in adipose tissue in vivo, and increases locomotor activity in other animal models. In granulosa cells, GHRF stimulates activity of plasminogen activator, playing a role in follicular development.
| Cas No. | 86472-71-1 |
|---|---|
| Purity | ≥95% |
| Formula | C225H361N77O66S |
| Formula Wt. | 5232.93 |
| Synonym | Somatotropin releasing hormone (1-43), Growth hormone releasing factor 43, Somatoliberin (rathypothalamus) (9CI); GHRF; GHRH |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | G2874 Info Sheet PDF |
|---|
Obál F Jr, Krueger JM. The somatotropic axis and sleep. Rev Neurol (Paris). 2001 Nov;157(11 Pt 2):S12-5. PMID: 11924022.
Liesman JS, McNamara JP, Capuco AV, et al. Comparison of growth hormone-releasing factor and somatotropin: lipid and glucose metabolism in dairy cows. J Dairy Sci. 1995 Oct;78(10):2159-66. PMID: 8598400.
Karakji EG, Tsang BK. Growth hormone releasing factor and vasoactive intestinal peptide stimulate rat granulosa cell plasminogen activator activity in vitro during follicular development. Mol Cell Endocrinol. 1995 Jan;107(1):105-12. PMID: 7796929.
Alvarez XA, Cacabelos R. Influence of growth hormone (GH) and GH-releasing factor on locomotor activity in rats. Peptides. 1993 Jul-Aug;14(4):707-12. PMID: 8234013.
LKT Labs
LKT实验室是一家专注于小分子的合成、纯化和分离的生化供应公司，用于研究应用。它的产品系列展示了已知的生物活性，在广泛的研究领域，特别是癌症和神经科学中得到了广泛的应用。这些产品包括蛋白激酶抑制剂、离子通道调节剂和激活剂。
LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators.
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名称 |
规格 |
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LKT Labs |
444912-48-5 |
(2-iodo-5-nitrophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone |
1mg 5mg 25mg |
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LKT Labs |
294646-77-8 |
(R)-CR8 |
1mg 5mg |
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LKT Labs |
2377-31-3 |
(Z)-1,-BIS(2-METHOXY-5-(TRIFLUOROMETHYL)PHENYL)DIAZENE OXIDE |
1mg 5mg 25mg |
