HygromycinBisanantibioticthatalsodisplaysantiviralactivity.Hygromycinbindsthe30Sribosomalsubunit,inhibitingproteinandRNAsynthesisofbacteriaorviruses;itinducesmisreADIngsatmultiplestepsinproteintranslationandsuppressestranslocation.Inanimalmodels,hygromycinBallowstranslationtooccurbutpreventsformationofviralantigenbyLeishmaniaand,separately,preventsinfectionbymurinehepatitisvirus.
| CasNo. | 31282-04-9 |
|---|---|
| Purity | ≥95.0% |
| Formula | C20H37N3O13 |
| FormulaWt. | 527.52 |
| IUPACName | 4-[3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6"-(1-amino-2-hydroxyethyl)-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2"-oxane]-3",4",5",7-tetrol |
| Appearance | BuffPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | H9726MSDSPDF |
|---|---|
| InfoSheet | H9726InfoSheetPDF |
BrodersenDE,ClemonsWMJr,CarterAP,etal.Thestructuralbasisfortheactionoftheantibioticstetracycline,pactamycin,andhygromycinBonthe30Sribosomalsubunit.Cell.2000Dec22;103(7):1143-54.PMID:11163189.
RoYT,ScheffterSM,PattersonJL.HygromycinBresistancemediateseliminationofLeishmaniavirusfrompersistentlyinfectedparasites.JVirol.1997Dec;71(12):8991-8.PMID:9371555.
MacintyreG,WoodsDE,AndersonR.HygromycinBinhibitssynthesisofmurinecoronavirusRNA.AntimicrobAgentsChemother.1991Dec;35(12):2630-3.PMID:1667257.
LKT Labs
LKT实验室是一家专注于小分子的合成、纯化和分离的生化供应公司，用于研究应用。它的产品系列展示了已知的生物活性，在广泛的研究领域，特别是癌症和神经科学中得到了广泛的应用。这些产品包括蛋白激酶抑制剂、离子通道调节剂和激活剂。
LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators.
|
品牌 |
货号 |
名称 |
规格 |
|
LKT Labs |
444912-48-5 |
(2-iodo-5-nitrophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone |
1mg 5mg 25mg |
|
LKT Labs |
294646-77-8 |
(R)-CR8 |
1mg 5mg |
|
LKT Labs |
2377-31-3 |
(Z)-1,-BIS(2-METHOXY-5-(TRIFLUOROMETHYL)PHENYL)DIAZENE OXIDE |
1mg 5mg 25mg |
