Danazolisaderivativeofthesyntheticsteroidethisteronethatisclinicallyusedtotreatendometriosisandhereditaryangioedema;italsopromotespregnancyinfemalesubjectsundergoinginvitrofertilization.Danazolinhibitsproductionofgonadotropinssuchasluteinizinghormone(LH)andfollicle-stimulatinghormone(FSH)andweaklyactivatestheandrogenreceptor.
| CasNo. | 17230-88-5 |
|---|---|
| Purity | ≥98% |
| Formula | C22H27NO2 |
| FormulaWt. | 337.46 |
| ChemicalName | (17α)-Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol |
| Synonym | Bonzol;Chronogyn;Danatrol;Danocrine;Danol;Ladogal;Winobanin |
| MeltingPoint | 224.4-226.8°C |
| Solubility | Solubleinchloroform,acetone.Sparinglysolubleinethanol.Insolubleinwater(0.001mg/mL) |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | D0253MSDSPDF |
|---|---|
| InfoSheet | D0253InfoSheetPDF |
FüstG,FarkasH,CsukaD,etal.Long-termefficacyofdanazoltreatmentinhereditaryangioedema.EurJClinInvest.2011Mar;41(3):256-62.PMID:20955212.
KusakabeK,MorishimaS,NakamutaN,etal.EffectofdanazolonNKcellsandcytokinesinthemouseuterus.JReprodDev.2007Feb;53(1):87-94.PMID:17077583.
MurakamiK,NomuraK,ShinoharaK,etal.Danazolinhibitsaromataseactivityofendometriosis-derivedstromalcellsbyacompetitivemechanism.FertilSteril.2006Aug;86(2):291-7.PMID:16806212.
FloydWS.Danazol:endocrineandendometrialeffects.IntJFertil.1980;25(1):75-80.PMID:6104649.
LKT Labs
LKT实验室是一家专注于小分子的合成、纯化和分离的生化供应公司，用于研究应用。它的产品系列展示了已知的生物活性，在广泛的研究领域，特别是癌症和神经科学中得到了广泛的应用。这些产品包括蛋白激酶抑制剂、离子通道调节剂和激活剂。
LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators.
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品牌 |
货号 |
名称 |
规格 |
|
LKT Labs |
444912-48-5 |
(2-iodo-5-nitrophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone |
1mg 5mg 25mg |
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LKT Labs |
294646-77-8 |
(R)-CR8 |
1mg 5mg |
|
LKT Labs |
2377-31-3 |
(Z)-1,-BIS(2-METHOXY-5-(TRIFLUOROMETHYL)PHENYL)DIAZENE OXIDE |
1mg 5mg 25mg |
