Cheirolin is an isothiocyanate (ITC) that exhibits antioxidative activity. Cheirolin is a sulfonyl analog of iberin. Like others ITCs, cheirolin induces phase II enzymes. In vitro, cheirolin increases activation and expression of Nrf2 as well as expression of heme oxygenase 1 (HO-1) and γ-glutamylcysteine synthetase.
| Cas No. | 505-34-0 |
|---|---|
| Purity | ≥97% |
| Formula | C5H9NO2S2 |
| Formula Wt. | 179.26 |
| Chemical Name | 1-Isothiocyanato-3-(methylsulfonyl)-propane |
| IUPAC Name | 1-isothiocyanato-3-methylsulfonylpropane |
| Melting Point | 47.5°C |
| Solubility | Slightly soluble in water, ether; freely soluble in alcohol, chloroform, ethyl acetate. |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | C2816 Info Sheet PDF |
|---|
Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058.
LKT Labs
LKT实验室是一家专注于小分子的合成、纯化和分离的生化供应公司，用于研究应用。它的产品系列展示了已知的生物活性，在广泛的研究领域，特别是癌症和神经科学中得到了广泛的应用。这些产品包括蛋白激酶抑制剂、离子通道调节剂和激活剂。
LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators.
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品牌 |
货号 |
名称 |
规格 |
|
LKT Labs |
444912-48-5 |
(2-iodo-5-nitrophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone |
1mg 5mg 25mg |
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LKT Labs |
294646-77-8 |
(R)-CR8 |
1mg 5mg |
|
LKT Labs |
2377-31-3 |
(Z)-1,-BIS(2-METHOXY-5-(TRIFLUOROMETHYL)PHENYL)DIAZENE OXIDE |
1mg 5mg 25mg |
