Description
Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats.
Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats.
| Cas No. | 61413-54-5  | 
|---|---|
| Purity | ≥98%  | 
| Formula | C16H21NO3  | 
| Formula Wt. | 275.35  | 
| IUPAC Name | 4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone  | 
| Synonym | ZK62711  | 
| Melting Point | 128-129°C  | 
| Solubility | Soluble in DMSO (warm 25mg/ml), ethanol (25 mg/ml warm).  | 
| Appearance | White to off-white powder  | 
| Store Temp | Ambient  | 
|---|---|
| Ship Temp | Ambient  | 
| Info Sheet | R5745 Info Sheet PDF  | 
|---|
Hu S, Cao Q, Xu P, et al. Rolipram stimulates angiogensis and attenuates neuronal apoptosis through the cAMP/cAMP-responsive element binding protein pathway following ischemic stroke in rats. Exp Ther Med. 2016 Mar; 11(3):1005-1010. PMID: 26998028.
Li YF, Huang Y, Amsdell S, et al. Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus. Neuropsychopharmacology. 2009 Oct; 34(11):2404-2419. PMID: 19516250.
LKT Labs
	
LKT实验室是一家专注于小分子的合成、纯化和分离的生化供应公司,用于研究应用。它的产品系列展示了已知的生物活性,在广泛的研究领域,特别是癌症和神经科学中得到了广泛的应用。这些产品包括蛋白激酶抑制剂、离子通道调节剂和激活剂。
	
LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators.
	
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