Description
VidarABIneisalong-actingantiviraloriginallyfoundinthemarinespongeTethyracrypta.VidarabineisanadenosineanaloginwhichtheD-riboseconstituentisreplacedbyD-arabinose,preventingformationofphosphodiesterbridgesuponincorporationintoDNA.ThiscompoundisasubstrateforandinhibitorofviralDNApolymeraseandmayalsoinhibitribonucleotidereductase.VidarabineisusedtotreatsubjectswithseverechronicEpstein-Barrvirus,herpessimplexvirus,orhumanpapillomavirus,aswellasimmunocompromisedpatientswithadenovirus-inducedhemorrhagiccystitis.
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