Description
Abacavir is a guanosine nucleoside analog reverse transcriptase inhibitor (NRTI) that is clinically used to treat HIV infection. Abacavir exhibits antiviral activity. This compound also inhibits guanylyl cyclase and telomerase activity.
Abacavir is a guanosine nucleoside analog reverse transcriptase inhibitor (NRTI) that is clinically used to treat HIV infection. Abacavir exhibits antiviral activity. This compound also inhibits guanylyl cyclase and telomerase activity.
Cas No. | 136470-78-5 |
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Purity | ≥98% |
Formula | C14H18N6O |
Formula Wt. | 286.33 |
IUPAC Name | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol |
Appearance | White to off white powder |
Store Temp | Ambient |
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Ship Temp | Ambient |
Info Sheet | A0401 Info Sheet PDF |
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Brochures | Antivirals Booklet |
Leeansyah E, Cameron PU, Solomon A, et al. Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging. J Infect Dis. 2013 Apr;207(7):1157-65. PMID: 23303810.
Baum PD, Sullam PM, Stoddart CA, et al. Abacavir increases platelet reactivity via competitive inhibition of soluble guanylyl cyclase. AIDS. 2011 Nov 28;25(18):2243-8. PMID: 21941165.
Ribera E, Tuset M, Martín M, et al. Characteristics of antiretroviral drugs. Enferm Infecc Microbiol Clin. 2011 May;29(5):362-91. PMID: 21531048.
LKT Labs
LKT实验室是一家专注于小分子的合成、纯化和分离的生化供应公司,用于研究应用。它的产品系列展示了已知的生物活性,在广泛的研究领域,特别是癌症和神经科学中得到了广泛的应用。这些产品包括蛋白激酶抑制剂、离子通道调节剂和激活剂。
LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators.
品牌 |
货号 |
名称 |
规格 |
LKT Labs |
444912-48-5 |
(2-iodo-5-nitrophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone |
1mg 5mg 25mg |
LKT Labs |
294646-77-8 |
(R)-CR8 |
1mg 5mg |
LKT Labs |
2377-31-3 |
(Z)-1,-BIS(2-METHOXY-5-(TRIFLUOROMETHYL)PHENYL)DIAZENE OXIDE |
1mg 5mg 25mg |