LKT/(+)-CATECHIN/C0278/1 mg,LKT Labs,,LKT Labs,lktlabs,+,,Array.Array.Array蚂蚁淘厂家直采.

ProductIDC0278

CasNo.154-23-4

Purity≥99%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

CatechinisaflavanoloriginallyfoundinCamillaandotherplantsources;itexhibitsantioxidative,anti-aging,anti-atherosclerotic,anti-ulcerative,neuroprotective,neuromodulatory,anticancerchemotherapeutic,andchemopreventiveactivities.CatechinincreaseslifespaninCaenorhaBDitiselegansandinhibitsmonoamineoxidaseB(MAO-B)invitro.Catechindecreasesatheroscleroticlesionarea,suppressesleukocyteadhesion,andinhibitsLDLoxidationanduptakeinanimalmodelsofatherosclerosis.Inanimalmodelsofbrainhemorrhage,catechinincreasersactivityofNrf2andphaseIIdetoxifyingenzymes,inhibitingoxidativestress,neurologicaldeficits,andlesionformation.Inotheranimalmodels,catechininhibitshistidinedecarboxylase,decreasinggastriclesionformation.Additionally,catechinincreasesmusclefatigueresistanceandexercisecapacityinvivo.ThiscompoundalsodecreasestumornumberandformationandsuppressesphosphorylationofFAKinanimalmodelsofcolorectalcancer.

ProductInfo

CasNo.	154-23-4
Purity	≥99%
Formula	C₁₅H₁₄O₆
FormulaWt.	290.27
ChemicalName	(2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
IUPACName	(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
Synonym	Catechol;Catechinicacid;Dexcyanidanol;Cyanidol;Catergen
MeltingPoint	93-96°C
Solubility	Solubleinhotwater,alcoholacetone,andglacialaceticacid.
Appearance	Faintlybrownpowder

ShippingandStorage

StoreTemp	-20°C
ShipTemp	Ambient

Downloads

MSDS	C0278MSDSPDF
InfoSheet	C0278InfoSheetPDF
Brochures	GreenTeaFlyer
Brochures	NaturalProductsFlyer

References

ChangCF,ChoS,WangJ.(-)-EpicatechinprotectshemorrhagicbrainviasynergisticNrf2pathways.AnnClinTranslNeurol.2014Apr1;1(4):258-271.PMID:24741667.

NogueiraL,Ramirez-SanchezI,PerkinsGA,etal.(-)-Epicatechinenhancesfatigueresistanceandoxidativecapacityinmousemuscle.JPhysiol.2011Sep15;589(Pt18):4615-31.PMID:21788351.

SaulN,PietschK,MenzelR,etal.CatechininducedlongevityinC.elegans:fromkeyregulatorgenestodisposablesoma.MechAgeingDev.2009Aug;130(8):477-86.PMID:19501612.

AuclairS,MilenkovicD,BessonC,etal.CatechinreducesatheroscleroticlesiondevelopmentinapoE-deficientmice:atranscriptomicstudy.Atherosclerosis.2009Jun;204(2):e21-7.PMID:19152914.

HouWC,LinRD,ChenCT,etal.MonoamineoxidaseB(MAO-B)inhibitionbyactiveprinciplesfromUncariarhynchophylla.JEthnopharmacol.2005Aug22;100(1-2):216-20.PMID:15890481.

WeyantMJ,CarothersAM,DannenbergAJ,etal.(+)-Catechininhibitsintestinaltumorformationandsuppressesfocaladhesionkinaseactivationinthemin/+mouse.CancerRes.2001Jan1;61(1):118-25.PMID:11196148.

MangiapaneH,ThomsonJ,SalterA,etal.Theinhibitionoftheoxidationoflowdensitylipoproteinby(+)-catechin,anaturallyoccurringflavonoid.BiochemPharmacol.1992Feb4;43(3):445-50.PMID:1540202.

ReimannHJ,LorenzW,FischerM,etal.Histamineandacutehaemorrhagiclesionsinratgastricmucosa:preventionofstressulcerformationby(+)-catechin,aninhibitorofspecifichistidinedecarboxylaseinvitro.AgentsActions.1977Mar;7(1):69-73.PMID:871094.

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