Description
This compound is a derivative of cephalomannine, found in species of Taxus. Like other taxanes, this compound may inhibit DNA polymerase and microtubule depolymerization, exhibiting anticancer activity.
This compound is a derivative of cephalomannine, found in species of Taxus. Like other taxanes, this compound may inhibit DNA polymerase and microtubule depolymerization, exhibiting anticancer activity.
Purity | ≥90% |
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Formula | C45H55NO14 |
Formula Wt. | 833.92 |
Appearance | White to off white powder |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | T0116 MSDS PDF |
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Info Sheet | T0116 Info Sheet PDF |
Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.
Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.
Pandey RC, Yankov LK, Poulev A, et al. Synthesis and separation of potential anticancer active dihalocephalomannine diastereomers from extracts of Taxus yunnanensis. J Nat Prod. 1998 Jan;61(1):57-63. PMID: 9461653.
LKT Labs
LKT实验室是一家专注于小分子的合成、纯化和分离的生化供应公司,用于研究应用。它的产品系列展示了已知的生物活性,在广泛的研究领域,特别是癌症和神经科学中得到了广泛的应用。这些产品包括蛋白激酶抑制剂、离子通道调节剂和激活剂。
LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators.
品牌 |
货号 |
名称 |
规格 |
LKT Labs |
444912-48-5 |
(2-iodo-5-nitrophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone |
1mg 5mg 25mg |
LKT Labs |
294646-77-8 |
(R)-CR8 |
1mg 5mg |
LKT Labs |
2377-31-3 |
(Z)-1,-BIS(2-METHOXY-5-(TRIFLUOROMETHYL)PHENYL)DIAZENE OXIDE |
1mg 5mg 25mg |